Tadalafil Tablets (generic Cialis)
1. What is Tadalafil?
Brand name: Cialis
Mechanism of action: Tadalafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. Nitric oxide then activates the enzyme guanylate cyclase, which results in increased concentrations of cGMP. Cyclic guanosine monophosphate causes smooth muscle relaxation in the corpus cavernosum thereby allowing inflow of blood.
2. What does Tadalafil do for erectile dysfunction?
Tadalafil is rapidly absorbed after oral administration. It helps increase erection duration during intercourse. The usual duration can last up to 36 hours.
3. Is Tadalafil FDA approved?
Yes, Tadalafil is FDA approved for erectile dysfunction.
4. Is Tadalafil safe to use?
Yes, but there are side effects for people with certain medical conditions. You should not use Sildenafil if you take any of the following types of medications: nitrates, blood pressure, cardiac, heart rate, HIV, antifungal
You should not use Tadalafil if you have any of the following medical conditions: coronary artery disease, aortic stenosis, structural heart disease, cardiac abnormal rhythms, heart failure, low blood pressure, stroke, priapism, sickle cell disease, or HIV.
Side effects may include:
- Visual disturbance
- Low blood pressure
- Heart attack
- Abnormal heart rhythm